Your FEV1 can be normal or not but if your FEF 25-75 is lower then you have a Reactive Airway Disease. Sometimes they call it small airways disease.
Also take a look at: "It is concluded that small airways disease is related to destruction of peribronchiolar alveoli, and it is postulated that small airways disease has a direct role in the causation of centrilobular emphysema."
http://www.steadyhealth.com/encyclopedia/Small_airways_disease
Goggle small airways disease and you can learn a lot on how the FEF25-75 plays on the final results.