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�?Diet �?/A> : Broccoli
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 Message 1 of 3 in Discussion 
From: Rene  (Original Message)Sent: 3/14/2006 7:40 PM

 

 


Broccoli

A recent study revealed that compounds found in broccoli may help to inhibit a certain type of bacteria that is associated with ulcers. In laboratory analysis, the chemical sulphoraphane, found in broccoli, killed the common ulcer-causing bacteria called Helicobacter pylori.  [RealAge.com]

A compound found in broccoli, cabbage, and brussels sprouts may hold the key to thwarting the herpes virus, according to preliminary research presented Sunday at the 43rd annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICACC) in Chicago. The new findings may be one more reason to make broccoli one of your five to nine servings of fruit and vegetables each day.

Preliminary lab studies of monkey and human cells found that d-indole-methanol (DIM), a compound found naturally in broccoli and other cruciferous vegetables such as cabbage and brussels spouts, may interfere with factors that stimulate cells to reproduce. The researchers found that DIM can inhibit herpes simplex virus, which also requires these factors to reproduce.

In their study, the researchers first treated human and monkey cells with DIM. They then infected the cells with one of two strains of the herpes virus, either HSV-1, which can cause either oral or genital herpes, or HSV-2, which causes genital herpes. The researchers also infected the cells with a herpes virus strain known to be resistant to the current available drug therapy, Zovirax.

DIM blocked the virus from reproducing by at least 99.9%, according to lead researcher Terri Stoner, a graduate student at Northeastern Ohio Universities College of Medicine in Rootstown, Ohio. 'DIM appeared to inhibit various types of the herpes virus,' Stoner tells said. 'And because it is found naturally in foods, the compound appears to be safe.'

 


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 Message 2 of 3 in Discussion 
From: ReneSent: 6/12/2006 10:17 PM
 


The Cancer-Fighting Power of Veggies Work With Your Genes
 
 
 Cruciferous vegetables like broccoli and cauliflower contain compounds that reduce the risk of hereditary cancers. The beneficial compound in these vegetables is sulforaphane (SFN).

Researchers have known that the compound can fight cancer caused by carcinogens, but now they've found it also fights those caused by genetics.

The researchers used mice that had been specially bred to carry a mutation that switches off a gene that suppresses tumors (the same gene that's related to colon cancer development in humans). When the gene is inactivated, polyps that lead to tumors develop in the small intestine.

In the study, one group of mice was fed a diet supplemented with 300 parts per million (ppm) of SFN. Another group was fed a diet supplemented with 600 ppm of SFN.

Three weeks later, mice fed the 300-ppm diet had an average of 25 percent fewer polyps in the small intestine compared to mice fed no SFN. Polyps decreased 47 percent in the 600-ppm group.

The researchers believe SFN suppressed certain enzymes that are active in mice and humans with colon cancer. They recommended that SFN be evaluated clinically for its cancer-preventative effects in humans.
 
 

Science Blog May 17, 2006
 
Dr. Mercola's Comment:

 
 No major news here.

Both broccoli and cauliflower are on the list of the 25 disease-fighting and highly recommended vegetable list. It is important to keep in mind that although these vegetables contain many healthy benefits, they might actually throw off your biochemistry if they don't fit in with your metabolic type.

To give you an idea of this, I am a protein metabolic type and broccoli pushes my biochemistry in an unhealthy direction. So, it helps me to avoid it, and that is what my body tells me to do.

However, the DIM (Diindolylmethane) found in broccoli is also in other cruciferous vegetables such as cauliflower, which happens to be good for protein types.

So it is very important to understand your body at a deeper level because if you were to eat broccoli and you were a protein type, the other effects of broccoli might push your metabolic biochemistry in the wrong direction and thus override the benefits of the DHT inhibition.

The best way to understand specifically what foods are ideal for your body in particular is to learn your metabolic type. Properly eating for your particular metabolic type will lead to increased daily energy, improved emotional well-being, a feeling of satisfaction and, of course, optimized health and weight so you live longer.

You'll also understand how beneficial eating generally healthy foods like broccoli really is compared to other foods that might be even better for you.

However, even if you were a mixed or vegetarian/carb type and broccoli were good for you, there are likely better ways to get the benefits than eating whole broccoli.

Growing broccoli sprouts yourself is easy and inexpensive. You can purchase organic broccoli seeds and your local library or health food store may have some instructions on sprouting seeds.

The other major benefit of the sprouts is that they don't smell, as you don't have to cook them. They are eaten raw, usually as an addition to salad. I suspect that there are similar benefits for many of the other vegetables when eaten as sprouts.

If you are interested in really leveraging this approach I would highly recommend adopting the use of broccoli spouts. I advocated this approach nearly 10 years ago now and wrote a detailed article about how you can inexpensively grow your own broccoli sprouts.

  
 Related Articles:

Broccoli Sprouts Fight Ulcers and Cancer

Chemicals in Broccoli and Other Veggies Cut Lung Cancer Risk

The Cancer-Fighting Power of Broccoli Sprouts
 



 
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Reply
 Message 3 of 3 in Discussion 
From: ReneSent: 8/9/2008 5:40 AM

Broccoli can reverse diabetic heart damage, say researchers

By Shane Starling

08-Aug-2008 - A UK study has found consuming broccoli can reverse damage caused to the heart blood vessels of diabetics due to the presence of a sulfur compound.

Researchers from the University of Warwick concluded the compound could function as a “dietary activator�? and thereby “prevent biochemical dysfunction and related functional responses of endothelial cells induced by hyperglycemia�?

Endothelial cells are those that form a thin layer on the interior of blood vessels. Their dysfunction is a major cause of morbidity and mortality among diabetics and has also been linked to problems such as kidney disease.

Hyperglycemia is the condition of having elevated blood sugar levels.

Findings

Lead researcher Professor Paul Thornalley and his colleagues found the compound �?sulforaphane �?provoked production of a protein called nrf2 that was beneficial to blood vessel health, even those damaged by hyperglycemia.

Thornalley’s team observed a 73 per cent reduction of Reactive Oxygen Species (ROS), which are commonly known as free radicals. ROS levels have been known to increase by as much as 300 per cent in diabetics.

“Our study suggests that compounds such as Sulforaphane from broccoli may help counter processes linked to the development of vascular disease in diabetes,�?said Thornalley.

“In future, it will be important to test if eating a diet rich in Brassica vegetables has health benefits for diabetic patients. We expect that it will.�?

A free-radical reducing, antioxidant effect was observed among the incubated human endothelial cells kept in low and high glucose concentrations (five and 30mM). Activation of nrf2 was assessed by nuclear translocation.

The presence of sulforaphane doubled the activation of nrf2.

“Sulforaphane prevented hyperglycemia-induced activation of the hexosamine and protein kinase C pathways, and prevented increased cellular accumulation and excretion of the glycating agent, methylglyoxal,�?the researchers wrote.

The study adds to a small but growing body of evidence demonstrating the potential for Brassica vegetables such as broccoli, Brussels sprouts, suedes, turnips and cabbages to benefit diabetic conditions.

Other studies have shown their consumption can ward off the onset of diabetes.

One such study conducted at the Tulane University School of Public Health and Tropical Medicine in New Orleans found increased intake of green leafy vegetables may reduce the risk of women developing type-2 diabetes.

Published in the journal Diabetes Care, the epidemiological study of 71,346 female nurses found for every additional serving of green leafy vegetables, the risk of developing diabetes may be reduced by almost 10 per cent.

The study followed the women, none of whom had diabetes, heart disease or cancer at the start of the study, for 18 years.

An estimated 19 million people are affected by diabetes in the EU 25, equal to four per cent of the total population. This figure is projected to increase to 26 million by 2030.

In the US, there are over 20 million people with diabetes, equal to seven per cent of the population. The total costs are thought to be as much as $132 billion, with $92 billion being direct costs from medication, according to 2002 American Diabetes Association figures.

Source:

Diabetes; Published online August 4, 2008, as db06-1003

"Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease"

[http://www.nutraingredients-usa.com/layout/set/print/content/view/print/216021]