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�?Supplements : VITAMIN E ~ good for .......
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 Message 1 of 2 in Discussion 
From: Rene  (Original Message)Sent: 11/14/2007 6:57 PM
 A collection of other articles can be found further down on the supplements page
 

THE WONDERS OF VITAMIN E 
 
Vitamin E is a fat-soluble vitamin and a powerful antioxidant that has been touted for its numerous potential health benefits. Vitamin E can help you stay healthy and fight some of the most common and deadly diseases. Research has shown that vitamin E may help prevent or mitigate the effects of chronic diseases such as heart disease, cancer, Alzheimer’s disease, and diabetes.

The National Health and Nutrition Examination Survey III (NHANES III) found that 27% of whites, 41% of African-Americans, 28% of Mexican Americans, and 32% of other had low levels of vitamin E.

This is quite tragic since the studies show that vitamin E is one of the most important and perhaps the best health insurance you can buy for the money!

Several population studies have shown that vitamin E levels may be more predictive of the risk of a heart attack or stroke than total cholesterol levels. Some studies show that high cholesterol levels are predictive of a heart attack 29% of the time. High blood pressure was predictive 25% of the time. However, low levels of vitamin E were predictive 70% of the time.13

Reduces the Risk of Heart Disease by A whopping 30 to 40%

A number of studies have associated lower rates of heart disease with higher vitamin E intake. The largest study to date on vitamin E and heart disease was conducted by researchers at Harvard University. The study looked at approximately 90,000 nurses and their intake of vitamin E. The results suggested that the incidence of heart disease was 30 to 40% lower among nurses with the highest intake of vitamin E from diet and supplements.

Very similar results were found in approximately 40,000 men in the Health Professionals Follow-up study. The men who took vitamin E supplements reduced their risk of heart disease by 37%.

A daily dose of 400 to 800 IU of natural vitamin E cut subsequent heart attacks in men with heart problems by an astonishing 77%. Other research shows it takes 400 IU �?00 I.U. of vitamin E to squelch toxicity (oxidation) of LDL cholesterol.14


Lowers Risk for all Mortality by 27%!!!!!! No Drug Can Match This

An extensive study of approximately 11,000 seniors done at the National Institute of Aging found that elderly people who supplemented with Vitamin E had a 27% lower risk of all-cause mortality, a 41% reduction in heart disease, and a 22% reduction in death from cancer. Vitamin E may also protect against the development of some cancers. Some evidence associates higher intake of vitamin E with a decreased incidence of cancer.


Reduces the Risk for Colon Cancer by 66%

The Iowa Women’s Health Study has demonstrated a very strong protective effect for vitamin E. This was a large scale, four-year study of 35,000 women between 55 and 66 years of age who had no previous history of cancer. The results revealed convincingly that a high intake of vitamin E was associated with a reduced risk of colon cancer. Risk of colon cancer was reduced by 66% for women taking the highest amount of vitamin E. I routinely recommend taking 400 to 800 IU’s a day.


Reduces Risk of Bladder Cancer by 40%

In almost all of the cases, the women with a high intake of vitamin E were taking supplements. The American Cancer Society recently released the results of a long-term study that evaluated the effect of vitamin E and C supplements on bladder cancer mortality. The study followed 1,000,000 adults for a 15-year period and found that those who regularly consumed vitamin E supplements for at least 10 years were 40% less likely to die from bladder cancer.


Vitamin E Benefits Those with Alzheimer’s

In one study, patients with moderately severe Alzheimer’s disease were studied for two years. The patients were given either large doses (2,000 IU) of vitamin E, Eldepryl (selegiline hydrochloride), or a placebo for two years. In the patients who received vitamin E, there was a significant delay in disease progression. This study shows that Alzheimer’s patients may live longer and remain in better health if they take high doses of vitamin E.


Vitamin E Benefits Those with Diabetes

Diabetes mellitus is one of the most common diseases in the world. Researchers have found that oxidative damage may play a strong role in the damage to tissues caused by diabetes as well as in the complications of diabetes. The results show that when these patients took 400 IU’s of vitamin E daily, they reduced their risk of heart attack by 43% and their risk of dying of heart disease by 55%. Since cardiovascular disease is the major cause of death in people with diabetes, vitamin E may have a strong, positive impact on health outcomes in diabetics.


Vitamin E Lowers Cancer Risk in Smokers

Scientists from the National Cancer Institute, working together with scientists in Finland, studied 30,000 male smokers in Finland. They found that of those who took a Vitamin E capsule every day for five to eight years, there was a 30% reduction in the cases of prostate cancer and a 40% reduction of deaths from prostate cancer. This is really exciting because in this country we expect about 40,000 men to die from prostate cancer this year.


Vitamin E, Multivitamins, and Alzheimer’s

Not a single older person who took separate doses of vitamin E (200-800 IU) or vitamin C (500-1000 mg) developed Alzheimer's disease during a four-year, double blind study. Subjects who took multivitamin supplements with low doses of vitamin E (typically 30 IU) or vitamin C (60 mg) had no reduction in risk of Alzheimer's. 15


Boosting the Immune System with Vitamin E

Taking 200 IU of natural vitamin E daily boosted immune functioning in older people. A supplement with only 60 mg of vitamin E daily did not improve immune functioning. Obviously, superior immune functioning lessens infections, possibly cancer, and heart disease. 16


Prevent Heart Attacks with Vitamin E

A daily dose of 400 to 800 IU of natural vitamin E cut subsequent heart attacks in men with heart problems by an astonishing 77%. Other research shows it takes 400 IU of vitamin E to squelch toxicity (oxidation) of LDL cholesterol.17


Longevity and Vitamin E

Taking vitamin E and vitamin C (in higher doses than in a multivitamin) cut chances of death from all causes by 42%. Vitamin E users were 47% less apt to die of heart disease and 59% less likely to die of cancer.18



Is Vitamin E Safe?

The Institute of Medicine and the federal government agree that vitamin E is safe at levels as high as 1600 IU per day for natural vitamin E (the form I recommend you use) or 1000 IU of synthetic vitamin E, the form most likely used in this study.


I recommend everyone take a good optimal daily allowance multivitamin mineral formula. [Any Multi-vitamin which] contains [only] 30 IU’s of vitamin E. There is a reason [some] multivitamins are so cheap - they’re worthless.


.......

If you wish to increase your vitamin E intake to 800 IU’s, which is not a bad idea, especially for anyone with heart disease, high blood pressure, stroke, diabetes, or cancer now or in their family history, please read why I recommend taking an additional one capsule of the readily absorbable, all-natural, mixed form of vitamin E.


Not all Vitamin E Supplements are the same!

On a supplement label, natural vitamin E is listed as d-alpha tocopherol, d-alpha tocopheryl acetate, or d-alpha tocopheryl succinate.

In contrast, synthetic forms of vitamin E are labeled with a dl-prefix.

Alpha-tocopherol is the most biologically active form of vitamin E, and its natural form consists of one isomer. In contrast, synthetic alpha-tocopherol contains eight different isomers, of which only one (about 12 percent of the synthetic molecule) is identical to natural vitamin E. The other seven isomers range in potency from 21 percent to 90 percent of natural d-alpha-tocopherol.

This may appear to be nerdy nutritional chemistry talk, but it is key to understanding how the body absorbs natural and synthetic supplements differently. Molecular structure determines how the body uses vitamin E.

Researchers have found that natural vitamin E assimilates and is absorbed far better than synthetic versions. Specific binding and transport proteins produced in the liver select the natural d-alpha form of vitamin E and largely ignore all other forms.

In one experiment, Japanese researchers alternately gave natural and synthetic vitamin E to seven healthy young women. It took 300 mg synthetic vitamin E to equal the blood levels achieved by a 100-mg dose of natural vitamin E.

In other studies at East Tennessee State University, Johnson City, researchers gave a variety of subjects either 30 mg/day or 300 mg/day vitamin E. In blood levels, natural vitamin E increased twice as much as the synthetic form in healthy subjects and pregnant women.

Researchers at Oregon State University, Corvallis, found the human body excretes synthetic vitamin E three times faster than the natural form.

By adding one capsule a day to your optimal daily allowance multivitamin you’ll help reduce your risk for certain life draining and life threatening illnesses.

From: Dr. Rodger Murphree's Newsletter, November 7, 2007

 



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Reply
 Message 2 of 2 in Discussion 
From: ReneSent: 1/23/2008 11:45 PM
 
 
 
Low vitamin E levels linked to greater physical decline
By Stephen Daniells
 

1/23/2008- Low blood levels of vitamin E are linked to greater physical decline in older people, suggests a new study from Yale University School of Medicine.

The researchers obtained measures for several micronutrients, including folate, vitamins B6, B12, D and E, but only the last vitamin was associated with physical decline for older persons, they report in the Journal of the American Medical Association.

"The current study provides empirical evidence that a low concentration of vitamin E is associated with subsequent decline in physical function in a population-based sample of older persons living in the community," wrote lead author Benedetta Bartali.

"Although the findings from this epidemiological study cannot establish causality, they provide a solid base that low concentration of vitamin E contributes to decline in physical function," she added.

Bartali and co-workers recruited 698 community-living people with an average age of 73.7 in Tuscany, Italy. A baseline examination was conducted from November 1998 through May 2000, and the subjects followed for three years. Physical performance was measured using the Short Physical Performance Battery, which included three objective tests of physical function.

Over this short time period, the researchers recorded a 1.1 point decline in physical performance, which exceeded the one point level needed to show a decline.

The researchers calculated on two determinants of physical decline: low vitamin E (alpha-tocopherol) levels among people aged between 70 and 80, and being older than 81. Levels of other micronutrients were not associated with declined levels.

"As the major lipid-soluble antioxidant, vitamin E plays a critical role in the defence from oxidative stress by donating electrons and neutralizing free radicals," wrote Bartali. "Low concentrations of vitamin E may affect this neutralization by creating an imbalance between oxidants and antioxidants and, consequently, a highly reactive milieu.

"Because molecular oxygen promptly accepts unpaired electrons to form reactive oxygen species, this imbalance may lead to excessive formation of reactive oxygen species and, consequently, to oxidative stress that may cause lipid peroxidation and DNA, muscle, and neuronal damage.

"This chain of events may explain, at least in part, our findings on the association between low concentrations of vitamin E and subsequent decline in physical function," she added.

The researchers go on to propose three mechanisms which could explain the relationship between low vitamin E levels and the decline in physical function: The increased level of oxidative stress could result in damage to muscle or DNA; there could be an exacerbation of atherosclerosis or other pathologic conditions; and an increase in neurodegenerative disorders.

Bartali and co-workers note that the subjects did not take vitamin supplements and added that they did not recommend vitamin E supplements to increase levels.

"Approximately 15 to 30 mg/d of dietary alpha-tocopherol [a component of vitamin E] is needed �?this amount can be easily reached through diet, from sources such as almonds, tomato sauce, and sunflower seeds among others," stated the researchers.

"Clinical trials may be warranted to determine whether optimal concentration of vitamin E reduces functional decline and the onset of disability in older persons with a low concentration of vitamin E," they concluded.

There are eight forms of vitamin E: four tocopherols (alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma, delta). Alpha-tocopherol (alpha-Toc) is the main source found in supplements and in the European diet, while gamma-tocopherol (gamma-Toc) is the most common form in the American diet.

Source: Journal of the American Medical Association
2008, Volume 299, Issue 3, Pages 308-315
"Serum Micronutrient Concentrations and Decline in Physical Function Among Older Persons"
Authors: B. Bartali, E.A. Frongillo, J.M. Guralnik, M.H. Stipanuk, H.G. Allore, A. Cherubini, S. Bandinelli, L. Ferrucci, T.M. Gill
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