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Insulin Question : What Does This Mean?
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Recommend  Message 1 of 3 in Discussion 
From: MrsMarried  (Original Message)Sent: 6/25/2007 7:23 AM
I was reading on the Lantus website tonight and came across this regarding kidney patients using Lantus. The following is what was on their website:
 
"reduced insulin metabolism due to renal impairment"
 
Does anyone know what this means? I'm sure that the answer is probably something simple but I have been searching and searching on the internet and can't find an answer. Thank you all for everything.


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Recommend  Message 2 of 3 in Discussion 
From: MSN Nicknamesafk1221Sent: 6/25/2007 1:29 PM
Patients with kidney disease are not as able to metabolize ANY insulin (not just Lantus) out of the blood stream.  What this creates is a condition where one is VERY sensitive to insulin.  Frequent hypos are often the result.  Case in point: ME!  I've had blood sugars as high as 250, and brought it down with as little as 1 unit of Humalog.  If I take 2, I'm likely to go to 40!  My dose of Lantus before be is 2 units.  My AM sugar today was 56.  But Lantus is neither the CAUSE of kidney disease, nor bad for kidney patients.  In fact, I was prescribed Lantus by a nephrologist when I was hospitalized in 2006 for my 3rd kidney transplant.  The surgery was a disaster, but I've been using Lantus ever since.  Even through the 2007 transplant which worked.  (my doses and my personal experience...I'm not a doctor, so I wouldn't presume to tell you what's best for YOU)
Hope that was helpful, and aleviated some of your concerns.  HUGS!  sheryl

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Recommend  Message 3 of 3 in Discussion 
From: MrsMarriedSent: 6/25/2007 9:26 PM
Sheryl,
 
Thank you for taking the time to explain this to me. I got worried when I read that on the Lantus website because my husband is a kidney patient. He is in renal failure with a kidney function of 26% -that's up from 16% though, thankfully.
He isn't having a problem right now with being very sensitive to insulin. His problem is that it seems like his insulin isn't working. He is taking 40 units nightly of Lantus and then Novlog through the day.
 
Anyway, thank you again for explaining this to me.
 
Smiles,
Amanda