Hi,
I've been on Byetta almost 3 months now. Month 1 was at 5ML and I had no major issues. Occasional nausea but nothing of importance. At the end of the first month had my follow up visit with my MD and we upped my dose to 10ML. Had a bit more nausea at first but by week 3 had an issue.
By the 6 week mark I had lost ~15lbs putting me ~185 and as my weight got under 185 I found that my blood sugars would drop really bad after my dose (which fits since my control is pretty tight once I'm under 185). The result seemed to indicate that I was overdosing in that I would take the dose and regardless of what I ate or did I was vomitting. So after about 4 or 5 days called the doc and stepped back down to the 5ML dose.
Doing fine on teh 5 ML dose have my 1st A1C next week and it should be back under 6 (was up to 6.2 when I went on Byetta).
My biggest problem to date is that I've had 2 of 3 pens that didn't dispense my does when I hit the plunger and instead wait until I twist the cap after I push it in. Rather annoying to have to sit there and manipulate the end of the pen while I sit there like a stuck pig.