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| | From: pray4acure2 (Original Message) | Sent: 11/8/2007 1:22 PM |
Ann N Y Acad Sci. 2007 Jun ;1107 :168-73 17804544
Autoimmunity in complex-regional pain syndrome.
[My paper] F Blaes , M Tschernatsch , M E Braeu , O Matz , K Schmitz , D Nascimento , M Kaps , F Birklein
Complex regional pain syndrome (CRPS) is an etiologically unclear syndrome with the main symptoms being pain, trophic and autonomic disturbances, and functional impairment that develops after limb trauma or operation and is located at the distal site of the affected limb. Because autoantibodies against nervous system structures have been described in these patients, an autoimmune etiology of CRPS is discussed. These autoantibodies bind to the surface of peripheral autonomic neurons. Using a competitive binding assay, it can be shown that at least some of the CRPS sera bind to the same neuronal epitope. Autoimmune etiology of CRPS is a new pathophysiological concept and may have severe impact on the treatment of this often chronic disease.
SOURCE: http://lib.bioinfo.pl/pmid:17804544 |
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Thank you for posting this. Someone just ask me if it affected us in this way and I did not know the answer. Sunshine |
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Glad you found it useful Sunshine. God bless you, (((gentle hugs))), Karly |
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