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Opiates
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Drug LAAM (Levomethadyl acetate hydrocholide)
Description This is the "super-methadone" increasingly showing up as an option at clinics since being approved by the FDA in 1993 for the maintainenance treatment of opiate addiction. LAAM's supposed advantage over methadone is that it last three times as long and thus can be administered only three times a week. (This is because LAAM breaks down slowly in the body into extremely long-acting metabolites.) On the other hand, federal regulations currently prohibit take-home dosing of LAAM, so clients using this drug cannot hope for fewer than three clinic visits weekly. Withdrawal is reputed to be an endless nightmare, so LAAM patients are thus rehabituated to methadone and withdrawn from that drug. Many patients reporting feeling that LAAM "holds" them less well than methadone, though LAAM advocates contend that sufficiently high doses of the drug must be maintained for effective treatment.
Member Monkeyboy (David C. Morrison)
 
Drug PROPOXYPHENE (Darvon, Darvocet, Dolene)
Description Patented by Lilly in 1955, propoxyphene is a cogener of methadone, though far less potent. Found in many medicine cabinets in the form of those red-and-grey Darvon capsules, Darvon is actually less potent (and euphoric in action) than codeine. It is, however, a very potent respiratory depressant, meaning that high dose abuse quite often leads to overdose. Intravenous injection is quite rough on the veins, and thus this practice is generally self-limiting. Mild withdrawal symptoms have occured after protracted use (800 mgs. or so over the course of two months). Has been used to moderate heroin withdrawal symptoms, but is not generally considered particularly effective in this role.
Member Monkeyboy (David C. Morrison)
 
Drug PENTAZOCINE (Talwin, Fortalgesic)
Description Patented in 1962, pentazocine belongs to the benzomorphan group of mixed agonist-antagonist opiate drugs. That means that it bonds to some opiate receptors but can unseat some already-consumed opiates binding to other receptors. Roughly one-third as powerful as morphine, pentazocine, is also of shorter duration. On the other hand, withdrawal symptoms are comparatively mild. At one time, Talwin was widely used on the street, particularly in combination with an antihystamine (an injected formulation nicknamed "Ts and Blues"). Talwin tablets have a high talc content, however, which causes talc deposits and lesions in the lungs when injected. Moreover, Winthrop has taken to formulating Talwin with naloxone, a pure opiate antagonist, which causes abrupt withdrawal symptoms when injected. Consequently, Talwin has pretty much fallen off the street drug map.
Member Monkeyboy (David C. Morrison)
 
Drug BUTORPHANOL (Stadol)
Description A cogener of the opiate alkaloid morphinan, butorphanol came into clinical use in the U.S. about 20 years ago. A mixed agonist-antagonist, this drug will not cause withdrawal symptoms in addicts with relatively low-tolerance habits, but caution is urged as use of agonist-antagonist drugs can precipitate dope sickness. Traditionally available solely in injectible solution, Stadol is also marketed (prescription only) in a nasal inhaler for relief of migraine pain. As such, it has reportedly led to no few cases of habituation and addiction. Withdrawal symptoms are comparatively mild and the drug's action, generally, is very similar to that of pentazocine (Talwin).
Member Monkeyboy (David C. Morrison)
 
Drug DETROMETHORPHAN (Romilar, Robitussin)
Description An isomer of the codeine analog of levorphanol, a semisynthetic mixed agonist-antagonist opiate, dextromethorphan (DMX) is neither analgesic nor addictive. For that reason, it is widely available in over-the-counter cough remedies. Although it is not a pleasure drug in the same way as its fellow opiates, DMX is often used by drug experimenters to achieve a bizarre dissociative state not unlike that caused by PCP. Like many others, I personally found its effects to be extremely unpleasant, though DMX does have its fans. Reportedly, tablets sold as Ecstacy sometimes contain DMX instead--and their rooked buyers have found themselves in for an unpleasant surprise.
Member Monkeyboy (David C. Morrison)
 
Drug NALOXONE (Narcan)
Description Patented in 1966, naloxone is a pure opiate antagonist, meaning that it rapidly unseats opiate molecules binding to the body's opiate receptors. Injection of naloxone (and it is ineffective by any other route) will rapidly reverse a potentially fatal heroin overdose. This is a very potent drug: 1 mg. of naloxone delivered intramuscularly will completely block the effects of 24 mg. of heroin. This effect will only last for 1-4 hours, however, and so the antagonist must be periodically readministered if the patient is overdosing on a longer last opiate (such as heroin or methadone). Besides restoring respiration, unfortunately, naloxone will also precipitate abrupt withdrawal symptoms in the habituated addict. This is a very unpleasant experience, but it beats dying. Although a prescription drug, naloxone is not scheduled. There is thus movement afoot to make Narcan available to using addicts in case of overdose emergencies. Until then, you must call EMS for naloxone when a friend is ODing.
Member Monkeyboy (David C. Morrison)
 
Drug NALTREXONE (Trexan, ReVia)
Description A much longer lasting pure opiate antagonist than naloxone, naltrexone also has the clinical advantage of being active orally. It is thus commonly prescribed to post-withdrawal opiate addicts in early recovery: though not remotely euphoric, this drug will block the effects of opiate agonists, such as heroin. Though not completely: It is possible to "shoot through" the naltrexone blockade, though at the danger of causing respiratory arrest if high doses of both drugs are present concurrently. Naltrexone is also now being administered in "depot" doses, placed under the skin, to achieve a long-lasting opiate blockade that does not depend upon the addict taking his naltrexone pill every day. Remarketed as ReVia, naltrexone is also being used in the treatment of alcoholism, on grounds that it diminishes the euphoria alcoholics experience from drinking.
Member
 
Drug FENTANYL (Sublimaze)
Description Developed in the early 1960s, this synthetic opioid is related to meperidine, though more powerful by orders of magnitude. Eighty times more potent than morphine, fentanyl is effective in microgram doses, though its effect is generally quite short-lived by comparison with other opiates. Available medically in injection form and transcutaneous patches (and fentanyl lollypops for the kids), this powerful opioid is the drug most commonly abused by medical addicts (doctors and nurses). Fentanyl cogeners manufactured by street chemists (most typically alpha-methyl-fentanyl) occasionally turn up on the cornrer marketed as "China White." Because it so potent, errors in cutting street fentanyl can lead to local epidemics of overdose.
Member Monkeyboy (David C. Morrison)
 
Drug
Subutex (Bupronorphine)
Description
Pretty much as per Bupronorphine except that this preperation is much longer acting and as such is beginning to be widely prescribed in the UK to heroin addicts.
However, before you can take a dose of Subutex you need to completely get all opiates out of your system or you will be thrown into severe withdrawlas.
I decided to try this substitute as I get no effect from methadone at all other than no withdrawals.
So I changed from methadone to Dihydrocodeine to get the meth out of my system. 8 hours after my last DF(60 hours after my last methadone dose) I took my first hit of Subutex. No effect. Over the next few days my Subutex build up was increased until I was at the max allowed to be prescribed. Still no europhoria. In fact I felt worse than I had on methadone. I gave the drug two weeks to see if it would begin to work for me. It didn't. Although I have heard it works for others.
Back to the methadone for me and back to misery with no euphoric drugs in sight.
Member Sibear
 
Drug
   HEROIN.
 
Hi   everyone  
    How r u all, great morning here, sunshine ,makes a change from rain.
     Can i add that in England, and i thought everywhere else,Heroin is also Diamorphine- Hydrochloride?  Thats the Pharmaceutical name,here anyway.
Sorry, i couldnt ADD it to the Edit  List on drugs.,i couldnt work how to use it.. Duh!.
ALSO,
    
Methadone is also called Physeptone.
I have a 500mls bottle in front of me now,[i just picked up my [weekly]  Methadone  script at the pharmacy..     ... ......the label states clearly that its Physeptone Mixture,Under that it says in smaller writing Methadone Mixture DTF  1mg in 1ml
and,
CONTAINS:
Methadone HydrochlorideBP
0.1%Sucrose ,
 [some ]E Numbers.[they are listed]
Ethanol  2.14%
Chloroform.....[never knew That!!!
Made at   Martindale Pharmaceuticals,Bampton Road,Romford ,England, ........So  freakin   what. !!!!!! ............  LOL....  but i just thought i,d add my two- pennyworth to give me  some stuff to write about.
 
also it [used to] come in   Glass Phials. 
  Physeptone   Ampoules,10mg in 1 ml
  For injection use ONLY.
OK.,  OK ..OKAYI will Stop now.......lol.......EnUFF Said.!
 
BUT we ALL call it Methadone now. ....and Heroin is still lovely Heroin whatever name its called,
 I am an old junkie,so give me a break,i am just [mentally] ,another version of Ossie Osbourne,[from Black Sabbath] and the Hit show, The Osbournes, tho i am fermale,  prettier  [God i hope so] and have NEver bit the head off a bat   or anything else.
See ya later,love ya.,xxxxxxxx
jinXie. 
 
Description
 
Member jinXie_junKie