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Methadone : hello,newbie here, not to meth
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(1 recommendation so far) Message 1 of 21 in Discussion 
From: MSN NicknameBouncyApril  (Original Message)Sent: 7/14/2003 8:23 PM
Hi all
I usually frequent the Watchdog methadone board,but found this which is cool cuz we discuss more than methadone. I was on methadone for a year and a half, and transferred to Bupe. I feel amazing. Energy, am losing weight, no nodding or dopiness, I have my emotions back (some of that can be overwhelming). Plus, the less you take, the less it costs, I can't see me weaning down the whole way on meth, paying $95/week for 1 or 2 mg of meth. Sickening. My husband stopped meth about 4 months ago, went down 5 mg a week until the end, and suffered alot of body aches for about a month. They told him he couldn't do it, so he did. He is that type. I couldn'lt believe it. I was so whimpy about it.Well, just wanted to say hi, and hope to contribute and learn from this board.
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Reply
 Message 7 of 21 in Discussion 
From: MarcoSent: 7/16/2003 11:53 PM
Hey grape- No I wasn't on meth before being on bup, but I have been on meth before and didn't use when I was on meth. I'm a professional also (or at least was until I lost my job about a year ago), I had a really successful 20 year career that's pretty much gone now.

I've got to straighten myself up so that I can get back to that career, or possibly choose another one.

No, you don't get sick from doing opiates on top of bup. It's not like naloxone or naltrexone. It's actually an opiate agonist/antagonist. It just blocks the high in the same way the methadone does. Even though you don't feel like you're on opiates, bup is a strong opiate. But apparently only if you shoot it. It's a major drug of abuse in some countries.

I really don't want to go on meth- the whole clinic thing is just too confining. I just need to get myself to where I'm not using on the bup. It does help with the cravings, a lot. I don't have those kind of cravings that you get when you just detox; but they're still strong enough that I haven't been able to quit completely.

You bring up a good point. Am I ready for it. Yes, I am. I need to get back to the person I used to be. And I think I can do that with bup. I've just got to stop giving into these cravings.

I guess it's a bit different for you cuz you were already stabilized on meth, and I came directly off using. How long have you been on bup for?

Marco

Reply
 Message 8 of 21 in Discussion 
From: MarcoSent: 7/16/2003 11:57 PM
Oh, just to clarify- bup is mixed with naloxone as you said, but naloxone only works if you shoot it. If you take it under the tongue (as when mixed with the bup) or just swallow it, it has no effect. That's why you don't get sick if you do opiates on top of bup. Believe me, I've been shooting dope once a week or so since I started on bup about 3-4 months ago. -Mark.

Reply
 Message 9 of 21 in Discussion 
From: MSN NicknameBouncyAprilSent: 7/17/2003 3:28 PM
hmmmmmmmm, Marc
I have been on Bupe for 3 weeks. Meth was a year and a half, and I did have
lapses with meth, a few. That's life, but no dirties:)
Bupe itself also competes with opiate receptor cites. It has nothing to do
with the Naloxone. Let me see if I can explain: Most of the opiates abused
are catagorized as mu opiod agonist drugs. They bind to the mu opiod site,
which there are several differnt types. Bupe and other drugs such as Stadol,
Talwin and Nubain are agonist/antagonist opiates and bind to the sigma
receptors. Each opiate sub receptor in the central nervous system is
responsible for a differnt therapeutic effect and or side effect/adverse
reaction. Mu is associates with responses such as supraspinal analgesia,
respiratory depression, euphoria, and drug dependence
Kappa; spinal analgesia, sedation, and pupillary constriction. Sigma;
anxiety, dyshporia, hallucinations, nightmares, and deltas which has not
been identified.
As before where it was mentioned agonist, this word means "to do" and
antagonist mean "to block".
it has been said that opiod agonist-antagonist work for and against. These
agents have both analgesic and opiate antagonistic efffects. It has been
suggested that Bupe, nubain, and talwin produce agonst effects at the kappa
and sigma receptors.
So, bupe competes with the some of these sites. So if you choose to shoot
and do bupe, no you won't get deathly ill, but the therapeutic effects of
the hit (the high) will be reduced. Especially in opiate addict patients
withdrwal symotoms my be precititated by co administration of bupe. and vice
versa. Try and experiment. Stop using the bupe for maybe two days, use the
same amount of hit as usual, see if it is stronger. It should be. Everyone's
exerience is different, but there is a definte adverse reaction between bupe
and dope if one is addicted to either. But how much of any of this is in our
heads? Alot.:)
I don't want to be a know it all, but I am an RN, BSN,C and the C is pain
management certification. I did a fellowship in pain and Pallliative care at
Memorial Sloan-Kettering Cancer Center and other projects. I am looking for
a position as a pain control liason for a hospital but most don't budget for
one nurse to just advise on pain. Docs think they know it all. However, this
knowledge has also given me the knowledge of how to abuse every opiate and
in every way. I got high as a kite after taking several Luvox with my
methadone dose. We drink grapefruit juice with our opiates, things you may
have heard are grounded in pharmacology. Well, I digress. If you are getting
high while on Bupe, you could be getting higher, and I would bet you are
using a pretty big shot. Just a guess.
I guess this makes me the class nerd. Please don't flame me. :( Most of my
info comes from the queens of pain control McCaffery and Pasero. It has
always been an interest. originally to learn how to best treat my elderly
patients, cuz I was sick of them getting darvocet and codeine. I have had to
prove myself to many docs and after a while some came around and let me use
a pain regimine of mine. Others did not. I find Opium, opiates, just
absolutely fascinating in every way. I would have loved to have been around
when there were opium dens. That is somethign I never did, I think I would
like that light mellow buzz. Well, I hope this makes sense. It probably
won't. It doesn't quite still to me .
Take care
Grapeape



The Irish are a fair people: they never speak well of one another

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Reply
 Message 10 of 21 in Discussion 
From: MSN Nicknamelifeoverkill23Sent: 7/17/2003 6:42 PM
DEAR GRAPE,
JUST READ YOUR REPLY TO MARC, YOU SURE DO STUDEY YOUR PHARMACOLOGY. AS I
SAID BEFORE IM AN RN TOO AND HAVE HAD THE FISTHAND EXPERIENCE OF THE SEVERE
ACUTE BUP REACTION IN DETOX, AND THE STADOL REACTION AS WELL. HOWEVER,
BEFORE I EVER USED DOPE STADOL WAS MY DRUG OF CHOICE AND GOT ME TOTALLY
WASTED!!!!!


>From: "grapeape" <[email protected]>
>Reply-To: "Heritics of Heroin" <[email protected]>
>To: [email protected]
>Subject: Re: hello,newbie here, not to meth
>Date: Thu, 17 Jul 2003 07:28:44 -0700
>

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Reply
 Message 11 of 21 in Discussion 
From: MarcoSent: 7/17/2003 8:56 PM
Hi grape: No, of course I won't flame you (and I don't think you're the class nerd). I'm impressed with your credentials and your knowledge. I've always considered myself fairly knowledgeable about opiates and the various receptors, neurotransmitters, etc. but it's always good to learn from someone who knows more. Anyway, I do follow what you're saying- to a point, then I got a little lost. My understanding of bup was that it was the agonist effect that did the blocking- just as meth (a pure agonist) blocks the receptors after a certain dosage. In effect (my understanding anyway) the agonist floods the receptors completely binding them so that more opiates, e.g. shooting H on top of taking bup does no good because there are no receptors left to bind to- the receptor sites are already occupied by the agonist that's already been ingested.

You're also right on another assumption- yes I'm doing a much larger shot than normal- one that would be a large shot for someone with a HUGE habit, and right again, I'm not feeling much from it. But if I understand what you're saying- it's (just for experimentation's sake) to not take the bup for a couple days, then shoot up (a smaller amount) and feel a high that I would feel as if I was a new user? Or is that taking it too far. Maybe I don't even want to know the answer to this?! as I am trying to quit and I'm not sure that knowing better ways to get high will be helpful. On the other hand.....

I truly hope that your search for work as a pain control liaison works out. I watched my father die from cancer over the six months from July 2002 - Jan 2003. He was very fortunate in that he had a wonderful oncologist who encouraged him to take all the pain medication he needed and wrote scripts ensuring he had enough. Unfortunately my dad was the very stoic type until very close to the end and needlessly sufferred pain cuz he felt taking "too much" pain medication was wrong- despite being urged by his oncologist and our family to take more.

It was only when it became intolerable- the last few days- that he started taking appropriate amounts of pain medication. On the other hand, he had a very dignified last six months of life and gave me a tremendous gift: to know how to die with courage and grace and dignity. So in the end, I guess it was his decision as to what was "enough." Yours is a truly worthy cause and I wish you all the best in your pursuit of it.

Marco.

Reply
 Message 12 of 21 in Discussion 
From: MarcoSent: 7/17/2003 9:04 PM
grape: also wondering if you're familiar with ibogaine and it's effect on neurotransmitters. I've been detoxed with it a couple of times and it is an amazing drug. While not even related to opiates it apparently occupies the same receptors (particularly mu) and offers an immediate detox. I've seen, with my own eyes, a couple of people who were on 400 mgs of methadone and several more on 200 - 250 mgs detoxed in 24 hours with no, absolutely no, withdrawal symptoms, or even post-acute withdrawal symptoms. It also prevents all cravings for a period of about two months (varies from person to person) as it turns from ibogaine to noribogaine and just sits for an extended time on the receptors and blocks all cravings- til the noribogaine wears off. A friend of mine is trying to patent a noribogaine patch which, I think, would be an unbelievable help to overcoming opiate addiction. Are you familiar with this? Marco.

Reply
 Message 13 of 21 in Discussion 
From: MSN NicknameBouncyAprilSent: 7/17/2003 10:44 PM
Marco,
I think the way you don't get high from meth is simply a high dose means
like you said alot of receptors are filled, but mainly, it just takes a
larger dose to get high. There is no ceiling effect though with meth.
Would you feel like a new user user after a few days of meth? Maybe once,
but you know it is never like the first time, never will be. I have a
problem with Ambien (night shift worker) and even after I don't take it for
like a month I still need at least 10-20 mg to get sleepy. Before a good old
5 mg tab did me fine and even made me feel drunk. It sucks how these thiings
happen. Quitting drugs is hard, I am watching my husband see why he started
doing drugs. He hates his job, he always gets dicked over (does flat rate
mechanic work and a bad service advisor means a bad paycheck for him) and
feels he never did what he should have with his intelligence (is a genius,
big whoop lol) He says he is turning into his father and he can't stand it.
With dope at least it was tolerable. I have him taking St. John's wort cuz
he won't go to the doc for depression and this will help him. He knows we
don't want back on juice.
As for Ibogaine, I have read about it somewhat and it seemed I saw the word
"hallucinogen" and was like nope not me! I did LSD many many times in my
teens and 20's and I think it warped some of my transmitters. As for
anything beyond that I quit reading. Something to look into, I don't
understand how it would work at all. Maybe you could teach me. :)
I am sorry about your grandfather, it is the modern way of man to be stoic.
I see it all the time. Either that or whine like crazy.



The Irish are a fair people: they never speak well of one another

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Reply
 Message 14 of 21 in Discussion 
From: MSN Nicknamelifeoverkill23Sent: 7/22/2003 12:16 AM
DEAR MARCO,

WHERE DOES ONE GET THIS IBOGAINE????IT SOUNDS AMAZING!!!!!!!!!!I WONDER IF
THEY DO CLINICAL TRIALS AROUND HERE, IT SOUNDS LIKE A GREAT WAY TO STAY OFF
METH.

BETH.


>From: "Heritics of Heroin" <[email protected]>
>Reply-To: "Heritics of Heroin" <[email protected]>
>To: "Heritics of Heroin" <[email protected]>
>Subject: Re: hello,newbie here, not to meth
>Date: Thu, 17 Jul 2003 13:04:03 -0700
>

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Reply
 Message 15 of 21 in Discussion 
From: MarcoSent: 7/24/2003 11:21 PM
Hey Beth-  Sorry, I didn't see your post 'til today.  Ibogaine is illegal in the US; there are no clinical trials, no nothing, and since it's a hallunogenic most people who are working with it feel it will never be legal in the US.
 
But there are places to get it.  I did it twice in St. Kitts under a study that was being done by the Univ or Miami.  They've completed the research and now are doing treatment there about 4x year.  There is also a clinic in Mexico just south of San Diego, and I've heard that there's one in Vancouver, BC.
 
It is an amazing experience.  A very spiritual experience- ibogaine comes from a plant that some tribes in Africa use as a rite of passage.  They keep you completely comfortable with a short-acting narcotic for the few days you're there before you take the ibogaine, no sickness at all.  Then the morning they give it to you they wait until you're dopesick.  Then basically you go on a 24-hour journey (during which you don't feel dopesick at all) and when you come down, you're no longer addicted.  Just like that.  Not even any post-acute withdrawal symptoms.  None.
 
And for a couple of months (for me anyway), I had no desire at all to use.  Someone could have put a big bag of H right in front of me and I would have had no interest.  This is a result of the ibogaine turning into noribogaine which remains in your system for 2-6 months.  The problem (again for me) was when the noribogaine wore off, the cravings came back and I started using again.  I hadn't done enough work on myself over that period of time to deal with the cravings coming back.  And they were upfront about it- that you wouldn't feel like using for awhile, but that eventually the cravings would come back.
 
It still was definitely worth it.  I've heard psychiatrists (who've done it) say that an ibogaine journey is like compressing 10 years of therapy into 24 hours.  You do an incredible amount of work on yourself while your on the ibogaine.  So even though I used again (both times) it was probably about the most powerful experience of my life.
 
Don't want to go on and on about it (as if I haven't already, but I could go on for pages), but if you're interested in knowing more you can e-mail me directly.
 
Marco

Reply
 Message 16 of 21 in Discussion 
From: MSN NicknameBouncyAprilSent: 7/25/2003 9:17 PM
okay, I have explained all the opiate receptor mumbo jumbo.
But Ibogaine eludes me.
How does this differ from LSD, shrooms or any other hallucinogen?
Since ectasy was used in therapy couldn't it be used too? What is the
difference?
And Marcos, don't feel bad, I have been having some wicked cravings on this
Bupe. Just started this week and I have been on about a month. the "trigger"
I think is a new job and working a slew of hours and being tired and beat
and sore. A "shot" would fix me right up. Thank god I haven't done it. The
question I beg is am I supposed to take more Bupe for this? I don't know if
anyone knows, but I imagine I should try. I took some on the way home and it
seemed to help a craving, but when I take a fast drive with some good loud
music, that works too, so I don't know which it was. I never had craving
problems, this sucks dick big time. I know if I would use I would feel like
a total piece of shit so what would be the point. I guess I am more of an
addict than I thought. Who would have guessed?
Lol
well, gotta go
grapeape



The Irish are a fair people: they never speak well of one another





>From: "Heritics of Heroin" <[email protected]>
>Reply-To: "Heritics of Heroin" <[email protected]>
>To: "Heritics of Heroin" <[email protected]>
>Subject: Re: hello,newbie here, not to meth
>Date: Thu, 24 Jul 2003 15:21:38 -0700
>
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Reply
 Message 17 of 21 in Discussion 
From: MarcoSent: 7/26/2003 4:18 PM
Hi Beth-  You probably understand the science better than I do.  But the action that ibogaine uses to eliminate withdrawal symptoms is unrelated to its properties as an entheogenic.  When I was in St. Kitts, the doc in charge explained that the way that ibogaine eliminates withdrawal symptoms is different from conventional opiate agonists, that ibogaine itself is not a dopamine or opioid agonist or antagonist.  But it attaches to a wide variety of recptor sites including kappa and sigma.  And apparently one other that they think is equally important for opiate withdrawal, the NMDA receptor site.  Within about 5-6 hours after its absorption it's transformed thru the liver into the metabolite noribogaine which continues to occupies these site for months.  Again, this is completely incidental to it being a hallucinogenic drug.  In fact one of the things they're working on is trying to patent a noribogaine patch- which would attenuate withdrawal and remove cravings without giving the hallucinogenic experience.
 
FYI ibogaine was "discovered" (although it's been used in Africa for hundreds of years) in the early '80s by some junkies in NY who wanted to try it for fun.  (Believe me, ibogaine is not something one would ever do for fun!)  When they came down from their trip, about 24 hours later, they found they weren't dopesick and had no desire to do any H.  Word got around and there was an underground movement throughout the 80s and early '90s.  And then in the early '90s some serious scientists started doing research on it.  The best place to look for all ibogaine info is www.ibogaine.org.  It has everything from it's history, the science behind it, all research that's been done to date- scientific as well as social science,etc.  You could also look on the internet for Dr. Deborah Mash, who's done more serious research on it than anyone.  About all I can add is that it is by far the most powerful drug I've ever taken and when I was younger I did a lot of the different hallucinogens- acid, shrooms, peyote, and they are MILD compared to ibogaine!
 
Re the bup, I'm on 32mg per day.  I started on 4 and since it wasn't really doing anything for my cravings the doc kept increasing it every week until I got to 32.  He says that above 32 there is no additive value.  So supposedly if your dose is less than that, increasing it should help with cravings.  I feel like if I could put together a month or so without using, I'd be OK.  That's how it was for me on methadone-  I kept using the first few months, but once I got a month or so without using, the cravings pretty much disappeared.  I'm going on vacation next week for about 3 weeks and so am hoping that will do it!
 
Marco. 

Reply
 Message 18 of 21 in Discussion 
From: MSN NicknameBouncyAprilSent: 7/27/2003 3:40 AM
Ibogaine sounds like no drug I have ever heard of. Very interesting. Not for
me, hallucinogens and me don't mix. but many have reported to me that they
have hallucinated on opiates mainly my patients.
I never have myself. Very intersting. Thanks for the info



The Irish are a fair people: they never speak well of one another





>From: "Heritics of Heroin" <[email protected]>
>Reply-To: "Heritics of Heroin" <[email protected]>
>To: "Heritics of Heroin" <[email protected]>
>Subject: Re: hello,newbie here, not to meth
>Date: Sat, 26 Jul 2003 08:18:58 -0700
>
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Reply
 Message 19 of 21 in Discussion 
From: MSN Nicknamelifeoverkill23Sent: 7/28/2003 12:15 PM
hey marco,

sorry to take so long to reply...the ibogaine sounds pretty cool,and
interesting, ill do some research on it myself. did you have any problems on
your journey?is there someone with you at all times or are you restrained.
you sound like a luck person to have experienced that. does anyone ever go
on the journey and "not return".

take care


>From: "Heritics of Heroin" <[email protected]>
>Reply-To: "Heritics of Heroin" <[email protected]>
>To: "Heritics of Heroin" <[email protected]>
>Subject: Re: hello,newbie here, not to meth
>Date: Thu, 24 Jul 2003 15:21:38 -0700
>

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Reply
 Message 20 of 21 in Discussion 
From: MarcoSent: 7/29/2003 8:18 PM
Hi lifeoverkill: Yeah, I did have a major problem on my first journey. I had what they call a 'dysphoric' journey, which is basically like a bad acid trip multiplied by about a billion. They ended up giving me some IV valium to calm me down and from that point on the journey was fantastic. The second journey was all good. Not fun, but gentle, and you learn an incredible amount about yourself.

In the program I was in there is ALWAYS someone with you. There are 2 beds in the room and each person has their own individual nurse who basically just sits and watches you to make sure there are no problems. You're not restrained, but one of the side effects of the drug is that it makes you ataxic, which is a fancy way of saying that basically you can't move. You pretty much lay completely still, without so much as moving a muscle for about 24 hours. After about 10 hours, the ataxia starts to wear off and the nurses will help you walk outside onto the porch to smoke some cigarettes or talk to the others who are on they're journey. But you're still pretty messed up at that point. Aside from the nurses, there is also always a doc in the next room and several other docs on the premises. But there's never been any kind of medical emergency- they're just very conscientous.

People always come back, because the drug wears off. There's never been a reported experiene of someone not coming back. But one of the things that freaked me out on my first journey was the thought that I wouldn't come back. And no matter what the doc told me, I didn't believe her. But eventually the bad part ended and the rest of the journey was incredible.

I am unbelievably lucky to have experienced this- it's not something many people have done.

Marco

Reply
 Message 21 of 21 in Discussion 
From: MSN Nicknamelifeoverkill23Sent: 7/31/2003 11:39 AM
dear marco,

thanks for the info, that seems really interesting.....you are lucky to
have done that. i wonder if the us will ever do that.

beth


>From: "Heritics of Heroin" <[email protected]>
>Reply-To: "Heritics of Heroin" <[email protected]>
>To: "Heritics of Heroin" <[email protected]>
>Subject: Re: hello,newbie here, not to meth
>Date: Tue, 29 Jul 2003 12:18:07 -0700
>

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