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General : The new "molecular signature" diseases.
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From: MSN NicknameHansSelyeWasCorrect  in response to Message 1Sent: 12/14/2007 4:03 AM
Here is what a major "expert" on hepatitis B (Baruch Blumberg) has pointed out about this "disease" (one of the "molecular signature" diseases) in his book "The hunt for a killer virus: Hepatitis B" (2002):

"Manfred [Bayer] is a paintstaking scientist with a meticulous approach to the craft of microscopy. It took him some time to select the correct shadowing methods for the preparations and to decide exactly where to look. In the ultracentrifuge fraction that contained the Australian antigen, he saw particles that were roughly circular, about 210 angstroms in diameter, and whose centers were, for the most part, empty. The particles were pretty small for a virus, but, as we concluded in our paper, they could be the sought-after hepatitis B virus." Page 108.

"...Lawrence Loeb... studied the physical and other charateristics of the particles. They did not contain nucleic acid, at least within the sensitvity of the tests we used." Page 109.

"Even now, when we know so much more than we did in the early days, it has not been possibe to grow HBV in conventional tissue cultures. Nor, for technical reasons we did not fully unravel, were the plaque assays feasible." Page 110.

When talking about the particles seen with the EM, he says: "There are many more of the noninfectious HBsAg particles (without DNA) in the blod than whole virus particles thare are infectious and can replicate..." Page 115.

I tried to find the text of a study Blumberg cited in the book, but it was not available online. However, another study that came later seems to be more on point. It can be found at:

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1930759

Any thoughts (especially from "Softrat")?


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     re: The new "molecular signature" diseases.   MSN NicknameHansSelyeWasCorrect  12/16/2007 5:50 AM