cody,
My approach is polyultrasonics. Any invader can be broken to pieces with the right set of frequencies, strengths, et hoc genus omne. Plaque could be broken up in an artery. The problem is plaque replaces much of the arteriol wall, so removing it removes needed tissue, like backflushing your cooling system in the car. In that, a "push-pull" time of device to generate the wave fields would need be generated and we'd have to rely on computers to time the sequences and synthesize the polyphonic waves. It also relies on total assessment of the person's genetic sequences. This can be accomplished through NMR then processed with programs like "BLAST" from Dr. James Kent (Cal Tech I think...)
My online time is limited as is my means to perform research beyond theory. Hope that changes this year...