I took a look at your first citation, but there was only a short abstract (full text requires paid subscription). Here is one passage: "...these results suggest that activated CD4+ T cells from untreated HIV+ individuals are in a hyper-proliferative state that is modulated by Type I interferons. From these results, we propose a new model for CD4+ T cell depletion during chronic HIV-1 infection."
It's not clear (at least to me) why this should lead to a drastic drop in CD4+T cell levels, especially many years after "infection." And they don't talk specifically of inflammation either. I did my own search and this was the closest I found:
"...it is possible that HIV-associated inflammation promotes smoking-induced lung carcinogenesis..."
Source: http://dceg.cancer.gov/veb/research/hivaids
|
Free Forum Hosting
Important Announcement
Prev Message
