QUOTE: ...Mobashery's team synthesized pieces of the cell wall of the bacterium Escherichia coli in his laboratory and was able to use the synthetic wall components to observe the chemical reactions that take place during the recycling process.
The researchers found that a member of the lytic transglycosylases family of enzymes known as M1tB performed the requisite cell wall fragmentation on the synthetic sample of the cell wall from their laboratory. They also were able to measure the rate of the transformation by M1tB, determining that 14,000 pieces of the cell wall are processed by each molecule of M1tB in one bacterial generation.
The product of the M1tB reaction on the cell wall is the entity that initiates the recycling event, but when it diffuses out of the bacterium, it causes the onset of the pro-inflammatory events associated with bacterial infections... UNQUOTE.
Source: http://www.sciencedaily.com/releases/2008/09/080908185322.htm |
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