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Nutrition : How polyunsaturated fatty acids (PUFAs) cause "heart disease."
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 Message 19 of 19 in Discussion 
From: MSN NicknameHansSelyeWasCorrect  in response to Message 18Sent: 9/26/2008 5:26 AM


QUOTE: Aspirin has become one of the most widely used medications in the world, owing to its ability to reduce pain, fevers, inflammation, and blood clotting. In animal studies, aspirin has also been shown to prevent atherosclerosis, though none of its known mechanisms of action would seem to account for this...

Using cell culture and mouse models, Sampath Parthasarathy and colleagues observed that aspirin –specifically its active byproduct salicylate�?can greatly increase the expression of two proteins: paraoxonase 1 (PON1) and apolipoprotein A1 (ApoA1); in the mouse studies, low dose aspirin supplements could increase PON1 and ApoA1 levels by 7- and 12- fold, respectively.

Both of these proteins are beneficial components of the HDL complex, the "good cholesterol" that helps prevent atherosclerosis; ApoA1 removes bad cholesterol from the bloodstream while PON1 is an antioxidant that breaks down toxic lipid peroxides... UNQUOTE.

Note that toxic lipid peroxides are not likely to be a problem if your only source of dietary fat was fresh coconut oil.

Source: http://www.sciencedaily.com/releases/2008/09/080922155916.htm