I was always 15-20 pounds fatter than I wanted to be until I went on Symlin 2 years ago. Symlin is an injectible drug for people who take insulin. It keeps you from getting hungry right after you eat, so you eat less. It also slows down digestion, which helps prevent post-prandial spikes in blood sugar. And it keeps the liver from releasing glucose when you take insulin, which used to mean taking more insulin, which also kept the pounds on. Anyhow, I lost 20 pounds with Symlin and have kept them off. I only wish this drug had been around when I was first diagnosed 25 years ago, but it has only been available a few years.
And for people not on insulin, there is Byetta, which does pretty much the same thing.
Julie