If you've read the posts on this thread and my comments elsewhere about the apparent role of cytokines in "AIDS," this new report will come as no surprise:
TITLE: Hodgkin Lymphoma: New Characteristics Discovered; Cytokines Help Tumor Cells Evade Immune System.
QUOTE: ...It has only been a few years since IL-21 was discovered in T cells. The function of IL-21, however, varies greatly depending on the kind of cell. In some cell types IL-21 stimulates the body's protection program, which researchers call programmed cell death or apoptosis. Each cell contains this apoptosis program so that it will self-destruct when it is altered or defective. This prevents the defective cell from damaging the entire organism.
Thus, IL-21 stimulates the T cells of the immune system and, for instance, drives cells of the chronic-lymphatic leukemia of the B-cell type (B-CLL) to apoptosis. By contrast, in T-cell leukemias, IL-21 does just the opposite and stimulates malignant growth. For the first time, the researchers from Berlin and Rome were able to show that IL-21 is produced by lymphatic cells originally derived from B cells. IL-21 activates a specific signaling pathway (STAT3), thus up-regulating the expression of a group of specific genes in HRS cells which support the unchecked growth and survival of HRS cells... UNQUOTE.
Source: http://www.sciencedaily.com/releases/2008/10/081008113432.htm
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