J Nutr Sci Vitaminol (Tokyo). 2006 Apr;52(2):83-8.
Dietary hydrogenated soybean oil affects lipid and vitamin E
metabolism in rats.
Naziroglu M, Brandsch C.
Institute of Nutritional Sciences, Martin-Luther-University of Halle-
Wittenberg, Halle/Saale, Germany. [email protected]
Fatty acids containing stearic acid, which are found in hydrogenated
fat, may have a detrimental effect on the cholesterol and
triacylglycerol (TAG) content of plasma lipoproteins, and on the
absorption of fatty acids and fat-soluble vitamins. The aim of our
study was to examine the tissue concentration of lipids and vitamins A
and E after feeding a hydrogenated soybean oil (HSO) diet to rats.
Twenty male Sprague-Dawley rats were randomly divided into two groups,
fed on coconut oil (control) and HSO, respectively in amounts
corresponding to 15% of the total feed. Plasma total cholesterol,
VLDL- and LDL-cholesterol, lipid peroxidation and daily excretion of
the TAG and cholesterol in feces were higher in the HSO than in the
control group. TAG values in plasma and liver, and HDL-cholesterol
levels in plasma were lower in the HSO than in the control group. The
same was true for phospholipids in plasma and for saturated fatty
acids, mono- and polyunsaturated fatty acids levels in the liver and
vitamin E in plasma, LDL and adipose tissue. The results of this study
provide new evidence concerning the effect of dietary hydrogenated fat
on lipid, TAG and vitamin E status, which are important for
maintenance of good health. Consumption of dietary HSO may be
associated with cardiovascular disease. |
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