MSN Home  |  My MSN  |  Hotmail
Sign in to Windows Live ID Web Search:   
go to MSNGroups 
Free Forum Hosting
 
Important Announcement Important Announcement
The MSN Groups service will close in February 2009. You can move your group to Multiply, MSN’s partner for online groups. Learn More
The Scientific Debate Forum.Contains "mature" content, but not necessarily adult.[email protected] 
  
What's New
  
  Disclaimer: Read this page first.  
  Links  
  Messages  
  General  
  Nutrition  
  "Mission Statement."  
  Why the "germ theory" is not science.  
  The Underlying Cause of "Disease."  
  The Scientific Method.  
  How dangerous are bacteria and viruses?  
  The Contributions of Hans Selye and others.  
  How direct effects are often ignored, and indirect markers used  
  Understanding "disease" at the molecular level.  
  Understanding disease at the molecular level, part II.  
  What the "common cold" can teach us about illness.  
  The AA connection to today's common "diseases."  
  How easy the key experiments would be to do.  
  The best practical diet and the explanation for it.  
  Fish oil quotes you might want to read  
  Where the "immune system" fits into this view of "disease."  
  How many 'scientific studies' violate the scientific method  
  Why you have to be careful with antioxidants.  
  Why Cancers today are more aggressive than those of the past.  
  The Latest Evidence.  
  Some studies worthy of note.  
  HSWC "in action."  
  How language can impede science.  
  How language impedes science, part II.  
  More on why "germs" don't cause "disease."  
  How a latent virus actually causes "disease."  
  A new report that "says it all."  
  The science "show" must go on?  
  Odds and ends  
  Some thoughts on a book by Robert Gallo.  
  Saturated fatty acids are the solution, not the problem.  
  It's stress, not "germs" that causes disease.  
  Epidemiology: Facts versus "factoids."  
  It's stress, not germs, part II.  
  The latest on "inflammation."  
  Why many nutritional claims make no sense  
  The use of hypotheticals in science.  
  What "viral infections" really do to the body.  
  What determines longevity?  
  An example of an anti-"saturated fat" study that is flawed.  
  A Rough Guide to a Gentle Diet.  
  A unified "AIDS" hypothsis without "HIV."  
  A unified "AIDS" hypothsis without "HIV." Part II.  
  Okay, so when is this diet going to kill me?  
  Scientific Debate Forum Pictures  
  The EFA Claim Was Refuted Long Ago  
    
  
  
  Tools  
 
Nutrition : How polyunsaturated fatty acids (PUFAs) cause "heart disease."
Choose another message board
View All Messages
  Prev Message  Next Message       
Reply
 Message 10 of 19 in Discussion 
From: MSN NicknameHansSelyeWasCorrect  in response to Message 9Sent: 1/10/2007 12:45 AM
Here is a passage from an essay written by fatty acid researcher Mary Enig, which provides some historical information that people often ask me about:

QUOTE: In the years that followed, a number of population studies demonstrated that the animal model—especially one derived from vegetarian animals—was not a valid approach for the problem of heart disease in human omnivores. A much publicized 1955 report on artery plaques in soldiers killed during the Korean War showed high levels of atherosclerosis, but another report—one that did not make it to the front pages—found that Japanese natives had almost as much pathogenic plaque�?5% versus 75%—even though the Japanese diet at the time was lower in animal products and fat.4 A 1957 study of the largely vegetarian Bantu found that they had as much atheroma—occlusions or plaque buildup in the arteries—as other races from South Africa who ate more meat.5 A 1958 report noted that Jamaican Blacks showed a degree of atherosclerosis comparable to that found in the United States, although they suffered from lower rates of heart disease.6 A 1960 report noted that the severity of atherosclerotic lesions in Japan approached that of the United States.7 The 1968 International Atherosclerosis Project, in which over 22,000 corpses in 14 nations were cut open and examined for plaques in the arteries, showed the same degree of atheroma in all parts of the world—in populations that consumed large amounts of fatty animal products and those that were largely vegetarian, and in populations that suffered from a great deal of heart disease and in populations that had very little or none at all.8 All of these studies pointed to the fact that the thickening of the arterial walls is a natural, unavoidable process. The lipid hypothesis did not hold up to these population studies, nor did it explain the tendency to fatal clots that caused myocardial infarction.

In 1956, an American Heart Association (AHA) fund-raiser aired on all three major networks. The MC interviewed, among others, Irving Page and Jeremiah Stamler of the AHA, and researcher Ancel Keys. Panelists presented the lipid hypothesis as the cause of the heart disease epidemic and launched the Prudent Diet, one in which corn oil, margarine, chicken and cold cereal replaced butter, lard, beef and eggs. But the television campaign was not an unqualified success because one of the panelists, Dr. Dudley White, disputed his colleagues at the AHA. Dr. White noted that heart disease in the form of myocardial infarction was nonexistent in 1900 when egg consumption was three times what it was in 1956 and when corn oil was unavailable. When pressed to support the Prudent Diet, Dr. White replied: "See here, I began my practice as a cardiologist in 1921 and I never saw an MI patent until 1928. Back in the MI free days before 1920, the fats were butter and lard and I think that we would all benefit from the kind of diet that we had at a time when no one had ever heard the word corn oil."

But the lipid hypothesis had already gained enough momentum to keep it rolling, in spite of Dr. White's nationally televised plea for common sense in matters of diet and in spite of the contradictory studies that were showing up in the scientific literature. In 1957, Dr. Norman Jolliffe, Director of the Nutrition Bureau of the New York Health Department initiated the Anti-Coronary Club, in which a group of businessmen, ranging in age from 40 to 59 years, were placed on the Prudent Diet. Club members used corn oil and margarine instead of butter, cold breakfast cereals instead of eggs and chicken and fish instead of beef. Anti-Coronary Club members were to be compared with a "matched" group of the same age who ate eggs for breakfast and had meat three times a day. Jolliffe, an overweight diabetic confined to a wheel chair, was confident that the Prudent Diet would save lives, including his own.

In the same year, the food industry initiated advertising campaigns that touted the health benefits of their products—low in fat or made with vegetable oils. A typical ad read: "Wheaties may help you live longer." Wesson recommended its cooking oil "for your heart's sake" a Journal of the American Medical Association ad described Wesson oil as a "cholesterol depressant." Mazola advertisements assured the public that "science finds corn oil important to your health." Medical journal ads recommended Fleishmann's unsalted margarine for patients with high blood pressure.

Dr. Frederick Stare, head of Harvard University's Nutrition Department, encouraged the consumption of corn oil—up to one cup a day—in his syndicated column. In a promotional piece specifically for Procter and Gamble's Puritan oil, he cited two experiments and one clinical trial as showing that high blood cholesterol is associated with CHD. However, both experiments had nothing to do with CHD, and the clinical trial did not find that reducing blood cholesterol had any effect on CHD events. Later, Dr. William Castelli, Director of the Framingham Study was one of several specialists to endorse Puritan. Dr. Antonio Gotto, Jr., former AHA president, sent a letter promoting Puritan Oil to practicing physicians—printed on Baylor College of Medicine, The De Bakey Heart Center letterhead.9 The irony of Gotto's letter is that De Bakey, the famous heart surgeon, coauthored a 1964 study involving 1700 patients which also showed no definite correlation between serum cholesterol levels and the nature and extent of coronary artery disease.10 In other words, those with low cholesterol levels were just as likely to have blocked arteries as those with high cholesterol levels. But while studies like De Bakey's moldered in the basements of university libraries, the vegetable oil campaign took on increased bravado and audacity.

The American Medical Association at first opposed the commercialization of the lipid hypothesis and warned that "the anti-fat, anti-cholesterol fad is not just foolish and futile. . . it also carries some risk." The American Heart Association, however, was committed. In 1961 the AHA published its first dietary guidelines aimed at the public. The authors, Irving Page, Ancel Keys, Jeremiah Stamler and Frederick Stare, called for the substitution of polyunsaturates for saturated fat, even though Keys, Stare and Page had all previously noted in published papers that the increase in CHD was paralleled by increasing consumption of vegetable oils. In fact, in a 1956 paper, Keys had suggested that the increasing use of hydrogenated vegetable oils might be the underlying cause of the CHD epidemic.11

Stamler shows up again in 1966 as an author of Your Heart Has Nine Lives, a little self-help book advocating the substitution of vegetable oils for butter and other so-called "artery clogging" saturated fats. The book was sponsored by makers of Mazola Corn Oil and Mazola Margarine. Stamler did not believe that lack of evidence should deter Americans from changing their eating habits. The evidence, he stated, " . . was compelling enough to call for altering some habits even before the final proof is nailed down. . . the definitive proof that middle-aged men who reduce their blood cholesterol will actually have far fewer heart attacks waits upon diet studies now in progress." His version of the Prudent Diet called for substituting low-fat milk products such as skim milk and low-fat cheeses for cream, butter and whole cheeses, reducing egg consumption and cutting the fat off red meats. Heart disease, he lectured, was a disease of rich countries, striking rich people who ate rich food. . . including "hard" fats like butter.

It was in the same year, 1966, that the results of Dr. Jolliffe's Anti-Coronary Club experiment were published in the Journal of the American Medical Association.12 Those on the Prudent Diet of corn oil, margarine, fish, chicken and cold cereal had an average serum cholesterol of 220, compared to 250 in the meat-and-potatoes control group. However, the study authors were obliged to note that there were eight deaths from heart disease among Dr. Jolliffe's Prudent Diet group, and none among those who ate meat three times a day. Dr. Jolliffe was dead by this time. He succumbed in 1961 from a vascular thrombosis, although the obituaries listed the cause of death as complications from diabetes. The "compelling proof" that Stamler and others were sure would vindicate wholesale tampering with American eating habits had not yet been "nailed down."

The problem, said the insiders promoting the lipid hypothesis, was that the numbers involved in the Anti-Coronary Club experiment were too small. Dr. Irving Page urged a National Diet-Heart Study involving one million men, in which the results of the Prudent Diet could be compared on a large scale with the those on a diet high in meat and fat. With great media attention, the National Heart Lung and Blood Institute organized the stocking of food warehouses in six major cities, where men on the Prudent Diet could get tasty polyunsaturated donuts and other fabricated food items free of charge. But a pilot study involving 2,000 men resulted in exactly the same number of deaths in both the Prudent Diet and the control group. A brief report in Circulation, March 1968, stated that the study was a milestone "in mass environmental experimentation" that would have "an important effect on the food industry and the attitude of the public toward its eating habits." But the million-man Diet Heart Study was abandoned in utter silence "for reasons of cost." Its chairman, Dr. Irving Page, died of a heart attack. UNQUOTE.

Source: http://www.westonaprice.org/knowyourfats/oiling.html


Replies to This Message The number of members that recommended this message.    
     re: How polyunsaturated fatty acids (PUFAs) cause "heart disease."   MSN NicknameHansSelyeWasCorrect  1/27/2007 7:51 AM