Wow, first paper of this kind in humans !!! This has been reported in many animal species, even in the same genus such as bees - the long lived queens increase oleic acid at the expense of PUFAs. I am not sure whether the trans-configuration is important but this clearly contradicts the other "correlation" studies citing high oleic acid in membranes and low PUFAs linked to obesity, insulin resistance, syndrome X etc.
If they find the mutation (or is it a behavioral trait e.g. that the PUFAs just taste bad to these people?) responsible for such difference they may directly test this hypothesis in a transgenic mouse ... |
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