DRUG INTERACTIONS: Acetaminophen is metabolized (eliminated by conversion to other chemicals) by the liver. Therefore drugs that increase the action of liver enzymes that metabolize acetaminophen [for example, carbamazepine (Tegretol), isoniazid (INH, Nydrazid, Laniazid), rifampin (Rifamate, Rifadin, Rimactane)] reduce the levels of acetaminophen and may decrease the action of acetaminophen. Doses of acetaminophen greater than the recommended doses are toxic to the liver and may result in severe liver damage. The potential for acetaminophen to harm the liver is increased when it is combined with alcohol or drugs that also harm the liver.

My suggestion to you  in an effort to help protect your liver is to take the supplement N-Acetyl Cysteine.

N-Acetyl Cysteine and Cancer

N-Acetyl CysteineN-Acetyl Cysteine has been shown to reduce the proliferation of certain cells lining the colon and may reduce the risk of colon cancer in people with recurrent polyps in the colon. Its action as an antioxidant and a glutathione precursor may also contribute to a protective effect against cancer.

N-Acetyl Cysteine Cautions

http://www.advance-health.com/nacetylcysteine.html

When taking N-acetyl cysteine it is recommended that two to three times as much Vitamin C be taken at the same time. Failure to do so may result in more harm than good from taking this product because of the prolonged presence of the oxidized form of L-Cysteine. Vitamin C also helps keep the glutathione that is produced from the Cysteine in its reduced form so that it can continue acting as an antioxidant.

My suggestion is to take a multiple vitamin with at least 150% of VITAMIN C; plus BUY a bottle of Vitamin C that is at least 100% vitamin C. This way you are helping to PROTECT the liver the most while taking  N-acetyl cysteine. swansonvitamins has NAC at a very good price but I cannot post their website according to MSN Code of Conduct!

Raymond