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General : New pain medication??
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 Message 1 of 7 in Discussion 
From: Jen, PT  (Original Message)Sent: 10/9/2008 5:12 PM


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Reply
 Message 2 of 7 in Discussion 
From: MSN NicknameCyndyK2Sent: 10/9/2008 5:19 PM
My question is, how do they know when mice are in pain? And if they can tell a MOUSE is hurting, why the hell can't they tell when PEOPLE are in pain?? That's just plain stupid. Something is seriously out of whack here, if they can tell mice are hurting but not people. I sure hope they make that work, and it doesn't turn out to be worse than morphine when it comes to side effects!

Cyndy

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 Message 3 of 7 in Discussion 
From: MSN NicknameAχPillSent: 10/9/2008 10:42 PM
You are sooooo right, Cyndy!!  I have been saying the same thing..."HOW CAN RATS TELL US "HOW" THEY ARE IN PAIN???" Generally  Dear Lord! 
 
Honestly, these are doctors, scientists, and biologists, opinions, not always facts.  We can do all the research we want it still remains.  It goes the same way, as our own doctors, true or not.
 
The only way if the pain medication, "will" work is the patient.
 
 

This statement is found HERE

"The team go on to show that brain activity in rats in areas related to feeling pain is much reduced when they received the same treatment. However, Prof Zeilhofer said that it is still too early to say when this new understanding will produce new treatments."

Well...that is my
 LOL
 

Reply
 Message 4 of 7 in Discussion 
From: Jen, PTSent: 10/9/2008 11:01 PM
I'm not sure how they assess pain in mice, but there is actually a wealth of information about pain centers in the brain.  The research study I was in a quite a few months back was measuring just that.  The scan is called an fMRI, or functional magnetic resonance image.  The study took a number of people with chronic pain, and had them use just their thoughts to increase or decrease the pain they are experiencing.  These techniques would be practiced outside of the fMRI to identify which phrases were best for each individual person at increasing or decreasing their level of pain.  Once they know what phrases work best, they put the patient in this scanner, and identify which areas of the brain are activated.  The posterior part of the anterior cingulate cortex is one such location.  The hypothalamus is also involved. 
 
This is a HUGE area of active research right now, and I think will continue its development for many years to come.  What I don't think they have yet been able to differentiate is pain from a psychological vs. physical source.  Also, exactly which parts of the brain identify acute vs. chronic pain, or does it even make a difference for treatment? I think once they get there, then medications for each type of pain can be more precise and thus beneficial for all the different kinds of pain out there.

Reply
 Message 5 of 7 in Discussion 
From: DanSent: 10/10/2008 12:33 AM
The mouse lays on it's genetically screwed up back, waves it's little feetsies in the air and squeels, "Ooooooooooowwwwwweeeeee!  Ooooooooooooowwwwweeeeeeee!..."  That's how they know.  /Nod 

Reply
 Message 6 of 7 in Discussion 
From: MSN NicknameThrashed_Arms_and_handsSent: 10/10/2008 8:32 PM
My question is, how do they know when mice are in pain? And if they can tell a MOUSE is hurting, why the hell can't they tell when PEOPLE are in pain?? That's just plain stupid. Something is seriously out of whack here, if they can tell mice are hurting but not people. I sure hope they make that work, and it doesn't turn out to be worse than morphine when it comes to side effects!
My question is, how do they know when mice are in pain? And if they can tell a MOUSE is hurting, why the hell can't they tell when PEOPLE are in pain?? That's just plain stupid. Something is seriously out of whack here, if they can tell mice are hurting but not people. I sure hope they make that work, and it doesn't turn out to be worse than morphine when it comes to side effects!
My question is, how do they know when mice are in pain? And if they can tell a MOUSE is hurting, why the hell can't they tell when PEOPLE are in pain?? That's just plain stupid. Something is seriously out of whack here, if they can tell mice are hurting but not people. I sure hope they make that work, and it doesn't turn out to be worse than morphine when it comes to side effects!
My question is, how do they know when mice are in pain? And if they can tell a MOUSE is hurting, why the hell can't they tell when PEOPLE are in pain?? That's just plain stupid. Something is seriously out of whack here, if they can tell mice are hurting but not people. I sure hope they make that work, and it doesn't turn out to be worse than morphine when it comes to side effects!
My question is, how do they know when mice are in pain? And if they can tell a MOUSE is hurting, why the hell can't they tell when PEOPLE are in pain?? That's just plain stupid. Something is seriously out of whack here, if they can tell mice are hurting but not people. I sure hope they make that work, and it doesn't turn out to be worse than morphine when it comes to side effects!
Adam

Reply
 Message 7 of 7 in Discussion 
From: MSN NicknameLitchukSent: 10/11/2008 2:16 PM
Dan!
 
It was Adam last week that's it im stopping reading the board when im eating or drinking that's another keyboard covered with my breakfast thanks to the image of the mouse waying it's paws in the ear and sweeking in pain!
 
mutter...mutter.... must invernt cherio proof keyboard...oh and coke proof it too.....
 
_James

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