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This is PART TWO of two pages of medication information.  Be sure to view part one.  Sorry that it's so wide, but am unable to increase length on this page. 

SOM-Medicines used by group members - Part two - FOR INFORMATIONAL PURPOSES ONLY this information is compiled from drug company information and empirical information from group members, and is edited and partial, and to be fully researched by the patient before considering use. SEE YOUR PHYSICIAN.

PART TWO
Drug Generic
Trade names

Manufacturer

Contraindications

Possible adverse reactions

Additional information

Alprazolam
Xanax

Generic
Purepac
Geneva
Brand
Pharmacia
Upjohn

Abrupt discontinuation, depression, elderly, psychosis, pulmonary disease, renal impairment, respiratory depression, sleep apnea, substance abuse, pregnancy

Agitation, amnesia, anorexia, appetite stimulation, confusion, constipation, dizziness, drowsiness, fatigue, hyper salivation, irritability, menstrual irregularity, tolerance, withdrawal

Acts at level of limbic, thalamic, hypothalamic regions of CNS. Mediated through inhibitory neurotransmitter gammaa-aminobutyric acid (GABA). Inhibits the ascending reticular activating system.

Carbamazepine
Tegretol
Carbatol
Epitol
Atretol

Generic
Purepac
Warner-Chilcott
Brand
NovartisAthenaNeurologica

Pregnancy, children, elderly, renal failure, liver insufficiency

Fatigue, drowsiness, diplopia, nystagmus, nausea. Sedation may occur for the first few days of therapy or following dosage increase. Instigate at lowest possible dosage, increase gradually to level of greatest benefit and fewest side effects.

Properties not fully understood. Blocks use-dependent sodium channels, inhibiting sustained repetitive firing. Reduces post-tatanic potentiation of synaptic transmissions in spinal cord. Pain relief associated with blockade of synaptic transmission in trigeminal nucleus.Metabolized in liver, excreted in urine and feces.Monitor: hemoglobin levels, liver function, CBC, serum carbamazepine concentrations.

Clonazepam Klonopin

Generic
Novopharm
Brand
Roche

Abrupt discontinuation is to be avoided

Confusion, depression, dizziness, drowsiness, fatigue, headache, mania, nightmares, psychological dependence, restlessness, tremor, vertigo, withdrawal

Benzodiazepine as anticonvulsant agent. Causes CNS depression. Block cortical and limbic arousal that occurs following stimulation of reticular pathways.Metabolized in liver, excreted in liver.

Cromolyn sodium
Nasalcrom
Others, as listed above in part one

Brand
Fisons
Bausch & Lomb
WarrickEtc.

Acute bronchospasm, cardiac disease, coronary artery disease, contact lens use (opthalmic solution)

Bronchospasm, cough, diarrhea, headache, lactose intolerance, nasal irritation, nausea, vomiting, hoarseness. Do not share product with other people.

Works at surface of mast cell to inhibit degranulation, preventing release of histamine. May reduce inflammation by inhibiting calcium influx, reduce hyperactivity of bronchi, inhibiting asthmatic response to cold air, allergens, environmental pollutants, or exercise

Gabapentin
Neurontin

Generic
Not available
Brand
Parke-Davis

Pregnancy, driving, operating machinery, elderly, renal impairmentAvoid us of antacids

Amnesia, anorexia, anxiety, appetite stimulation, back pain, blurred vision, constipation, depression, diplopia, dizziness, drowsiness, fatigue, irritability, nystagmus, tremor, vertigo

Exact action unknown, appears to interact with cortical neurons at auxiliary subunits of voltage-sensitive calcium channels. Not metabolized, excreted in urine. Monitor: WBC

Mometasone
NasonexElocon

Generic
Not available
Brand
Schering corp.

Children, fungal infections, glaucoma, infection, nasal trauma, pregnancy, viral infection, visual disturbance

Acmeiform rash, conjunctivitis, bronchospasm, cough, diarrhea, heavy menstrual bleeding, headache, impaired wound healing, rhinitis, sinusitis, skin irritation

Reduces allergic response of mast cells involved in allergic response. Reduces inflammation and edema. Inhibits release of histamine. Synthetic corticosteroid with anti-inflammatory, antiprurtic, vasoconstrictive properties.

Phenytoin
Dilantin

Generic
Mylan
Alpharma
UDL Labs.
Elinks-Sinn
Brand
Parke-Davis

Alcoholism, diabetes mellitus, elderly, fever, hematological disease, pregnancy, renal impairment, thyroid disease

Abdominal pain, anorexia, aplastic anemia, bullous rash, coma, constipation, dizziness, drowsiness, injection site reaction, jaundice, nausea, vomiting, nystagmus

Elevates seizure threshold and/or limits spread of seizure discharge. Limits spread of seizure activity, reduces seizure propagation. Mediated through effect on sodium channels on neuronal cell membrane. Less sedating than phenobarbital. Used to manage grand mal seizures and partial, psychomotor seizures. Used alone or in combination with phenobarbital or other anticonvulsants. Monitor: CBC, LFTs, MCV, serum albumin, serum phenytoin concentrations. Take with food.

Propranolol
Inderal
Betachron

Generic
Geneva
Inwood
Lederle
Sidmak
Brand
Wyeth-Ayerst
Inwood Labs.

Asthma, bronchitis, depression, elderly, emphysema, heart failure, pregnancy, angina, abrupt discontinuation, surgery (interacts with anesthesia drugs)

Diarrhea, fatigue, heart failure, hypoglycemia, libido decrease, muskoskeletal pain, nausea, vomiting, nightmares.

Beta blocker, competes with adrenergic neurotransmitters.

Topiramate
Topamax

Generic
Not available
Brand
Ortho-McNeil

Abrupt discontinuation, children, dialysis, driving, operating machinery, pregnancy, renal disease/ failure/impairment

Abdominal pain, agitation, anorexia, anxiety, aphasia, back pain, confusion, constipation, depression, diplopia, dizziness, drowsiness, menstrual irregularity, fatigue, sinusitis, tremor, visual impairment, weight loss

Exact mechanism unknown. May block spread of seizures, rather than raise seizure threshold. May block voltage-sensitive sodium channels. Derived from naturally occurring monosaccharide D-fructose. Has long duration of action and narrow therapeutic range. Not metabolized, excreted unchanged in urine.

Trileptal
Oxycarbazepine

Generic
Not available
Brand

 

 

 

Zonisamide
Zonegran

 

 

 

Generic
Not available
Brand
Elan Pharma

 

 

Abrupt discontinuation, dehydration, driving, operating machinery, pregnancy, renal disease/failure/impairment, sulfonamide hypersensitivity

 

Abdominal pain, agitation, anxiety, confusion, constipation, depression, diarrhea, diplopia, dizziness, drowsiness, fatigue, headache, insomnia, irritability nausea, vomiting, nystagmus, psychomotor impairment, rash, rhinitis, weight loss.Additional notes: ataxia, psychosis, speech impairment

 

Exact mechanism unknown. Appears to exhibit a dual mechanism of action as anticonvulsant by stopping spread of seizures and suppressing their focus. Acts at sodium and calcium channels. May block sodium channels and reduce voltage-dependent, transit-inward currents. Stabilizes neuronal membranes and suppresses neuronal hypersynchronization. Sulfonamide. Metabolized by acetylation and reduction, excreted in urine. Monitor: CBC, LFTs, serum creatinine/BUN, urinalysis.